Todd Duffee Returns to the Octagon at UFC 181 Against Anthony Hamilton

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After being forced away from mixed martial arts since 2012 due to a Parsonage-Turner syndrome diagnosis, Todd Duffee will return to the Octagon against Anthony Hamilton at UFC 181 on Dec. 6.

Ultimate Fighting Championship officials confirmed the bout to Sherdog.com after an initial report from ESPN.com. The pay-per-view takes place at Mandalay Bay Events Center in Las Vegas and features a pair of title fights, as Chris Weidman defends his middleweight strap against Vitor Belfort, and reigning lightweight king Anthony Pettis squares off with Gilbert Melendez.

Duffee has fought three times under the UFC banner, amassing a record of 2-1. The American Kickboxing Academy member defeated Tim Hague in his Zuffa debut at UFC 102 before losing to Mike Russow via knockout at UFC 114. Duffee then took a fight against Alistair Overeem in K-1, losing in 19 seconds before getting back on track against Neil Grove. The win propelled the 28-year-old back to the Las Vegas-based promotion, where he defeated Philip De Fries at UFC 155 before being diagnosed with the rare disorder.

Hamilton is coming off a TKO victory at UFC 177 against Ruan Potts. The win was “Freight Train’s” first under the UFC banner, following a loss in his promotional debut against Alexey Oleinik at UFC Fight Night “Swanson vs. Stephens.” Hamilton called for Brendan Schaub after his win in Sacramento, Calif., but a bout against the returning Duffee will have to suffice.